Basic Information
VIS ID
TVIS30000415
Fusion event
HIV-CGN integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
q21.3
Reference genome
GRCh37/hg19
Start
151510013/151537537 (Hg38)
End
151510013/151537537 (Hg38)
Orient
+
Location type
UTR3
Fragile sites / regions
FRA1F
Target gene
CGN
miRNAs that regulate target gene
hsa-mir-125b-5p ; hsa-mir-186-5p ; hsa-mir-19b-3p ; hsa-mir-7110-3p ; hsa-mir-6793-3p ; hsa-mir-4705 ; hsa-mir-6771-3p ; hsa-mir-1270 ; hsa-mir-143-5p ; hsa-mir-185-5p ; hsa-mir-202-3p ; hsa-mir-3163 ; hsa-mir-3663-5p ; hsa-mir-3944-5p ; hsa-mir-4306 ; hsa-mir-451b ; hsa-mir-4531 ; hsa-mir-4644 ; hsa-mir-5192 ; hsa-mir-548e-5p ; hsa-mir-6131 ; hsa-mir-620 ; hsa-mir-9-5p
Nearest miRNA
hsa-mir-101-1/Upstream/985523; hsa-mir-1182/Downstream/8259;
Nearest TSS
ENST00000473358/Upstream/1659; ENST00000461859/Downstream/2768;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/25895, chr1-CpG: 56/Downstream/2648
Upstream sequence
GGGTGACCCAATTATTCAGACCTAAGACAGGGAGGGGTCAGAGTGATGGTGATAAAAAAAAAAAATCATCAGCAATAAGCTGATAGATGGACTTTCCACT
Downstream sequence
GTAGGAGTGGACATTTCAAGCCAACTGAGCCTTTTCCTCAAGTGCCGACACCTCCCTCATCTCTCTTATAGTGGAAGGATGGTCAGCATTAGGCTGATGG
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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