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Viral Integration Site DataBase
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TVIS30000423
Basic Information
VIS ID
TVIS30000423
Fusion event
HIV-TAF1B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr2
Cytoband
p25.1
Reference genome
GRCh37/hg19
Start
10023107/9882978 (Hg38)
End
10023107/9882978 (Hg38)
Orient
-
Location type
Intronic
Target gene
TAF1B
miRNAs that regulate target gene
hsa-mir-580-3p
;
hsa-mir-5189-3p
;
hsa-mir-539-5p
;
hsa-mir-651-5p
;
hsa-mir-4266
;
hsa-mir-24-3p
;
hsa-mir-564
;
hsa-mir-383-3p
;
hsa-mir-4779
;
hsa-mir-4695-5p
;
hsa-mir-5571-3p
;
hsa-mir-6829-3p
;
hsa-mir-6791-3p
;
hsa-mir-2276-3p
;
hsa-mir-1304-3p
;
hsa-mir-1281
;
hsa-mir-4485-5p
;
hsa-mir-6890-3p
;
hsa-mir-154-5p
;
hsa-mir-4638-5p
;
hsa-mir-6741-3p
Nearest miRNA
hsa-mir-7158/Upstream/3232539; hsa-mir-10b/Downstream/309636;
Nearest TSS
ENST00000437798/Upstream/6980;
ENST00000602458/Downstream/53382;
Nearest CpG islands
None/Target,
chr2-CpG: 135/Upstream/39206
,
chr2-CpG: 184/Downstream/67800
Upstream sequence
TTGACTTATTATTTGGTGTTTTGTGTTTTATCCCAATATGGAACATCAGTCATAATTTAACGAAGAGTAGaattttattattttttattttCCTTATGTG
Downstream sequence
GATTCCTCTAATCCTTTAGGTTATCCTCAAAATATAGCTGTAGTGTGATGTGTGTGCATTGCAGATAGGTATGTTGTTGAGACTAAACTTGAGAACTTTT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
Sample Information
×
Sample name
ACH-2 Bulk Culture
Sample type
Cell line
Gender
Female
CpG Island Information
×
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