Basic Information
VIS ID
TVIS30000430
Fusion event
HIV-TRAK2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr2
Cytoband
q33.1
Reference genome
GRCh37/hg19
Start
202244018/201379295 (Hg38)
End
202244018/201379295 (Hg38)
Orient
-
Location type
UTR3
Fragile sites / regions
FRA2I
Target gene
TRAK2
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-193b-3p ; hsa-mir-9-5p ; hsa-mir-218-5p ; hsa-mir-19b-3p ; hsa-mir-19a-3p
Nearest miRNA
hsa-mir-10b/Upstream/12246184; hsa-mir-1244-1/Downstream/5403939;
Nearest TSS
ENST00000437798/Upstream/21897; ENST00000488196/Downstream/8563;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/260309, chr2-CpG: 110/Downstream/71835
Upstream sequence
CAACATTGAGAAAAAACAGATCTACTTCTTTCCATTTCTTAGCCTGTGTCAACTGCTGAATGCTGAAATCTAACCCCAGAGCCTCACTTTGCCATTTCAT
Downstream sequence
ACAGTTTGAATAAAAAAAAAGAACCTTAGAGAAAAAGAAAAAGCTTTGACTCCCCCATTAAAAAGTTTATTCTCTAATTCTATAAATATCAAGAAGGCAG
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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