Basic Information
VIS ID
TVIS30000433
Fusion event
HIV-TBC1D5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr3
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
17350595/17309103 (Hg38)
End
17350595/17309103 (Hg38)
Orient
+
Location type
Intronic
Target gene
TBC1D5
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-493-5p ; hsa-mir-4446-5p ; hsa-mir-3679-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-655-5p ; hsa-mir-361-3p ; hsa-mir-329-5p ; hsa-mir-6779-3p
Nearest miRNA
hsa-mir-12127/Upstream/375843; hsa-let-7g/Downstream/2005745;
Nearest TSS
ENST00000440867/Upstream/264911; ENST00000449613/Downstream/63031;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/423753, chr3-CpG: 58/Downstream/433467
Upstream sequence
ACATAAGTCTTTTTCTAAGGACTTCAGCTAGAATTCTATGTGATTCTAGCAAATAGCAAAGAATTAAAAATTCCAAATTTTTAGCACCATCAAATAGTAT
Downstream sequence
AGAATAACCTTTAAAAATTAGTTAAGAGATGTTAATTTTATGTAAATTTGAAACCAAATATAACCATTTGTGGGGTTAAAGCAAGGCAAAAAAAATTCAA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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