Basic Information
VIS ID
TVIS30000443
Fusion event
HIV-ROBO2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr3
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
76818339/76769188 (Hg38)
End
76818339/76769188 (Hg38)
Orient
+
Location type
Intronic
Target gene
ROBO2
miRNAs that regulate target gene
hsa-mir-145-5p ; hsa-mir-342-5p ; hsa-mir-514b-3p ; hsa-mir-514a-3p ; hsa-mir-6844 ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-8084
Nearest miRNA
hsa-let-7g/Upstream/1030825; hsa-mir-12124/Downstream/2738699;
Nearest TSS
ENST00000440867/Upstream/458092; ENST00000471893/Downstream/270698;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/862031, chr3-CpG: 63/Downstream/270159
Nearby gene
ROBO2(+270955) ;
Upstream sequence
TAGACTGCTACGTGGCAACACCTAGCAACCACACAAGTTTCCTTGACAGACCCAGTTGTTCTTTGTTTGGTAGATGTGATGATGCTCAAAGTATAGTAAG
Downstream sequence
ATCTGGCGACACTTGTTAAAATGTAAATGAAAAACGAATATATGTAGAACAACAGTTATTAGTAtttaatacacattcagattatgtggggatcttgtta
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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