VISDB - VIS Detail

Basic Information

VIS ID

TVIS30000451

Fusion event

HIV-SLC25A36 integration

Validated

Detection method

QiaQuick PCR and Sequencing

Data source

download(RID)

Sample type

Cell line

Disease

HIV-infected disease (HID)

Quality evaluation

Normal

Reported year

2016

PubMed ID

26912621

Virus Sequence

Virus name

HIV

Reference genome

K03455.1

Host Sequence

Chromosome

chr3

Cytoband

q23

Reference genome

GRCh37/hg19

Start

140689567/140970725 (Hg38)

End

140689567/140970725 (Hg38)

Orient

Location type

Intronic

Target gene

SLC25A36

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-222-3p ; hsa-mir-218-5p ; hsa-mir-3148 ; hsa-mir-4668-5p ; hsa-mir-5584-5p ; hsa-mir-26a-5p ; hsa-mir-26b-5p ; hsa-mir-1297 ; hsa-mir-4465 ; hsa-mir-25-3p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-363-3p ; hsa-mir-367-3p ; hsa-mir-92b-3p ; hsa-mir-577 ; hsa-mir-636 ; hsa-mir-4753-5p ; hsa-mir-6768-3p ; hsa-mir-569 ; hsa-mir-548c-3p ; hsa-mir-3153 ; hsa-mir-4302 ; hsa-mir-5094 ; hsa-mir-6733-5p ; hsa-mir-6739-5p ; hsa-mir-548n ; hsa-mir-548t-5p ; hsa-mir-548az-5p ; hsa-mir-1253 ; hsa-mir-4434 ; hsa-mir-4516 ; hsa-mir-4531 ; hsa-mir-4534 ; hsa-mir-5197-3p ; hsa-mir-5703 ; hsa-mir-8082 ; hsa-mir-187-5p ; hsa-mir-4426 ; hsa-mir-4647 ; hsa-mir-4662b ; hsa-mir-5692a ; hsa-mir-5697 ; hsa-mir-8066 ; hsa-mir-6733-3p ; hsa-mir-154-5p ; hsa-mir-4506 ; hsa-mir-3134 ; hsa-mir-4682 ; hsa-mir-3200-5p ; hsa-mir-7855-5p ; hsa-mir-580-3p ; hsa-mir-3678-3p ; hsa-mir-1273h-3p ; hsa-mir-3162-5p ; hsa-mir-9500 ; hsa-mir-6822-5p ; hsa-mir-6750-5p ; hsa-mir-4326 ; hsa-mir-221-3p ; hsa-mir-548v ; hsa-mir-6500-3p ; hsa-mir-3146 ; hsa-mir-9-3p ; hsa-mir-5690 ; hsa-mir-4803 ; hsa-mir-3650 ; hsa-mir-4480

Nearest miRNA

hsa-let-7g/Upstream/6532819; hsa-mir-1224/Downstream/10595151;

Nearest TSS

ENST00000440867/Upstream/360; ENST00000514629/Downstream/2941;

Nearest CpG islands

None/Target, chr3-CpG: 148/Upstream/27965, chr3-CpG: 117/Downstream/80319

Upstream sequence

TTCTGAATTCAGCTTAGACAGTAGAGAGCACCCTAAAGGATATTCTAAGTAGGTTGGGAAAGCAATTTATATTCATTTTGCTTTTAAAAGAATCTGTTAG

Downstream sequence

TTAAGGACAGAATTTGAGAATTCATATAGATTGGAAGTGAAGACAAATGTTTGTCGTATGTGAAAAGTGTAATATATACATAAATTAGTAGTTTATTTAT

Reference

Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.