Basic Information
VIS ID
TVIS30000457
Fusion event
HIV-DLG1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr3
Cytoband
q29
Reference genome
GRCh37/hg19
Start
197022112/197295241 (Hg38)
End
197022112/197295241 (Hg38)
Orient
+
Location type
Intronic
Target gene
DLG1
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-218-5p ; hsa-mir-9-3p
Nearest miRNA
hsa-let-7g/Upstream/1293; hsa-mir-922/Downstream/379255;
Nearest TSS
ENST00000440867/Upstream/34780; ENST00000414529/Downstream/1648;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/264738, chr3-CpG: 115/Downstream/2315
Nearest cancer related gene
DLG1(TSG, No orient, 0)
Upstream sequence
GGAGCTGGGTAACAGTTAAAAGGCAGTTCATTACACTGTGCTATGTATCCTTATGTTTTTAAAAGTCTATTAAAATGTTACATTTTTCAAAATTGTTCAG
Downstream sequence
GTGCATCAAGTGGTCTTTACAAAAATCTTTCATTCTAAAACCGTAGAGAGCATCCATTTATCAATAATGTACCTGACAGGACACACTGACTTGAAAGTAG
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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