Basic Information
VIS ID
TVIS30000467
Fusion event
HIV-CEP72 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr5
Cytoband
p15.33
Reference genome
GRCh37/hg19
Start
654848/654733 (Hg38)
End
654848/654733 (Hg38)
Location type
Intronic
Target gene
CEP72
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-5589-5p ; hsa-mir-6506-5p ; hsa-mir-4731-5p ; hsa-mir-619-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-433-5p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-6084 ; hsa-mir-4290 ; hsa-mir-1292-3p ; hsa-mir-1470 ; hsa-mir-150-5p ; hsa-mir-621 ; hsa-mir-8485 ; hsa-mir-3166 ; hsa-mir-585-5p
Nearest miRNA
hsa-mir-10397/Downstream/408163;
Nearest TSS
ENST00000502646/Upstream/1707; ENST00000514507/Downstream/722;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/8557, chr5-CpG: 95/Downstream/7435
Nearby gene
CEP72(+1182) ;
Upstream sequence
GGGATGGGGTTAATTTGTCATCACGTAATTTATGTATGTAAGAGTATTAGAAGATGTTAATATTAATCCACTTTAAGCTTATAGATgcttacctcgtttg
Downstream sequence
ggtttcattgagcttcttggacctgtgagttcatatttttcaccagatttggcaaagttgcagccactactcatatttcttgtctgaccccgtctctcac
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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