Basic Information
VIS ID
TVIS30000471
Fusion event
HIV-FYB1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr5
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
39272908/39272806 (Hg38)
End
39272908/39272806 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5A
Target gene
FYB1
miRNAs that regulate target gene
hsa-mir-4795-3p ; hsa-mir-613 ; hsa-mir-206 ; hsa-mir-1-3p ; hsa-mir-126-5p ; hsa-mir-4307 ; hsa-mir-656-3p ; hsa-mir-33a-3p ; hsa-mir-513c-3p ; hsa-mir-513a-3p ; hsa-mir-3606-3p
Nearest miRNA
hsa-mir-10397/Upstream/715245; hsa-mir-103a-1/Downstream/14678698;
Nearest TSS
ENST00000502646/Upstream/2149; ENST00000603514/Downstream/1666;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/197672, chr5-CpG: 39/Downstream/151984
Nearby gene
FYB1(-2149) ;
Upstream sequence
TAGTCATGCTACAATTTCCTCTCTATACCAGTAAGTTGGACACAAATTACATGATAAACAGGAATCTAGCAATTATTCAGTTAACAGTGTAATTTATTGG
Downstream sequence
GTAAGTCTCTGGTTAAGAGAACTTTGAATTTCAATTCATCCATCTAAATTCCATTTCAAGTTGTGCTTATTTCCAAATGCAGATTAAGGTAATTTTTAGT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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