Basic Information
VIS ID
TVIS30000478
Fusion event
HIV-FBXW11 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr5
Cytoband
q35.1
Reference genome
GRCh37/hg19
Start
171353583/171926579 (Hg38)
End
171353583/171926579 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5G
Target gene
FBXW11
miRNAs that regulate target gene
hsa-mir-148b-3p ; hsa-mir-450a-5p ; hsa-mir-16-5p ; hsa-mir-192-3p ; hsa-mir-6892-5p ; hsa-mir-6878-5p ; hsa-mir-504-3p ; hsa-mir-5703 ; hsa-mir-4516 ; hsa-mir-4434 ; hsa-mir-1909-5p ; hsa-mir-6770-5p ; hsa-mir-6760-5p ; hsa-mir-4475 ; hsa-mir-4433b-3p
Nearest miRNA
hsa-mir-10397/Upstream/539819; hsa-mir-10523/Downstream/735586;
Nearest TSS
ENST00000502646/Upstream/17720; ENST00000398186/Downstream/51177;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/296243, chr5-CpG: 97/Downstream/79421
Upstream sequence
ttctcatggtttaacaccaacccccttggtgctgtcgtggcatgagtgagtgagttctcacgagacctgattgtttaaaagtagcacctcaccactctct
Downstream sequence
cttcctcctgctccggccacacgaagtgcccgcttccccttcgccttctgccataattgaagccaagcagacgctgccatgcttcctatatagcctgcag
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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