Basic Information
VIS ID
TVIS30000479
Fusion event
HIV-PPARD integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr6
Cytoband
p21.31
Reference genome
GRCh37/hg19
Start
35329286/35361509 (Hg38)
End
35329286/35361509 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
PPARD
miRNAs that regulate target gene
hsa-mir-331-3p ; hsa-mir-92a-3p ; hsa-mir-29b-3p ; hsa-mir-218-5p ; hsa-mir-148a-3p ; hsa-mir-148b-3p ; hsa-mir-152-3p ; hsa-mir-205-3p ; hsa-mir-302c-3p ; hsa-mir-30a-3p ; hsa-mir-30d-3p ; hsa-mir-30e-3p ; hsa-mir-4276 ; hsa-mir-511-3p ; hsa-mir-520f-3p ; hsa-mir-6867-5p
Nearest miRNA
hsa-mir-1236/Upstream/1120773; hsa-mir-10398/Downstream/108999;
Nearest TSS
ENST00000381078/Upstream/18895; ENST00000229769/Downstream/90852;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/18600, chr6-CpG: 81/Downstream/90728
Upstream sequence
ggccaaggtgggagggtcacctgaggtcaggcatttgagatcaacctgggcaacgtagtgagacccagtgtctatttatttaaaaaaataaaataataat
Downstream sequence
aaaaaaAGAAAAATAACTTTAATGTTATTTTTGTCGTCCTCTTCATCTGAACATTGGCCTGCGTAGGTATTAACCTGAGTCCAGTGATTGTTTGTGGAGC
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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