Basic Information
VIS ID
TVIS30000483
Fusion event
HIV-UTRN integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr6
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
144758290/144437154 (Hg38)
End
144758290/144437154 (Hg38)
Orient
+
Location type
Intronic
Target gene
UTRN
miRNAs that regulate target gene
hsa-mir-206 ; hsa-mir-1-3p ; hsa-mir-21-5p ; hsa-mir-455-3p ; hsa-mir-505-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-let-7b-5p ; hsa-mir-3136-3p ; hsa-mir-4313 ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-1915-5p ; hsa-mir-6793-3p ; hsa-mir-4714-3p ; hsa-mir-203b-5p ; hsa-mir-3691-3p ; hsa-mir-556-3p ; hsa-mir-6718-5p ; hsa-mir-6801-5p
Nearest miRNA
hsa-mir-10398/Upstream/3753271; hsa-mir-1202/Downstream/6665521;
Nearest TSS
ENST00000381078/Upstream/93053; ENST00000367525/Downstream/146056;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/150010, chr6-CpG: 132/Downstream/1297606
Upstream sequence
tgattctcctgcatcagcctcccaagtagctgggactgcaaacatgtgccaccacgcccggctaattttttgtgtttttagttagagacggggtttcacc
Downstream sequence
ttgttgtccaggctggtcttgaactcctggcctaggtgatccacctgcctcagcctcccaaaatgctgggattataggtgtgagccaccacacccagccT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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