Basic Information
VIS ID
TVIS30000485
Fusion event
HIV-AMZ1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr7
Cytoband
p22.3
Reference genome
GRCh37/hg19
Start
2757736/2718102 (Hg38)
End
2757736/2718102 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA7B
Target gene
AMZ1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-186-5p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-877-3p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-324-5p ; hsa-mir-4304 ; hsa-mir-4469 ; hsa-mir-5193 ; hsa-mir-4667-3p ; hsa-mir-1470
Nearest miRNA
hsa-mir-339/Upstream/190957; hsa-mir-10399/Downstream/2070463;
Nearest TSS
ENST00000635602/Upstream/15572; ENST00000433945/Downstream/42350;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/15190, chr7-CpG: 21/Downstream/268
Nearby gene
AMZ1(+2666) ;
Upstream sequence
GCTCCACAATGGCCCTCAGAGGGTCCGCGGCAGCCAGGCCCGTCCAACCTCCTGCCCTCTCTGAGAGGGGCCCGAGCTCTCGCAAGATTAACCAGAGACG
Downstream sequence
ACACCTACCAGATTCCACCACTGAGGCCTCCCTCGATGCCTGCTCCCTGGGCTTTTTAATGAACGCACTTCTGTCACATGGAAACTGAGCCCGGCATGGA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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