Basic Information
VIS ID
TVIS30000488
Fusion event
HIV-SEPTIN7 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr7
Cytoband
p14.2
Reference genome
GRCh37/hg19
Start
35877117/35837507 (Hg38)
End
35877117/35837507 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7C
Target gene
SEPTIN7
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-429 ; hsa-mir-200a-3p ; hsa-mir-200c-3p ; hsa-mir-141-3p ; hsa-mir-200b-3p ; hsa-mir-26b-5p ; hsa-mir-34a-5p ; hsa-mir-135a-3p ; hsa-mir-296-3p ; hsa-mir-127-3p ; hsa-mir-587 ; hsa-mir-5581-3p ; hsa-mir-223-5p ; hsa-mir-4716-5p ; hsa-mir-511-3p
Nearest miRNA
hsa-mir-1183/Upstream/896673; hsa-mir-10399/Downstream/1081850;
Nearest TSS
ENST00000635602/Upstream/4709; ENST00000634700/Downstream/9253;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/35526, chr7-CpG: 87/Downstream/129894
Upstream sequence
GGTCATATTGTCAGGATAGTTAAaattgctagctagtattaatactataataacatcgttatagttatacctttgcttcaatttttatttattttcttag
Downstream sequence
aataataaagctttggaagtttgaattgctgttaagattgatgcattgatttaagggttttgatacataataccaaattgctctaaaacaagttgtgtac
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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