Basic Information
VIS ID
TVIS30000489
Fusion event
HIV-TNS3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr7
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
47461680/47422082 (Hg38)
End
47461680/47422082 (Hg38)
Orient
+
Location type
Intronic
Target gene
TNS3
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-21-5p ; hsa-mir-342-3p ; hsa-let-7i-5p ; hsa-mir-8070 ; hsa-mir-5003-5p ; hsa-mir-8485 ; hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-1178-3p ; hsa-mir-6071 ; hsa-mir-6749-3p ; hsa-mir-377-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-5088-3p
Nearest miRNA
hsa-mir-1183/Upstream/2540282; hsa-mir-10399/Downstream/9533703;
Nearest TSS
ENST00000635602/Upstream/18657; ENST00000429010/Downstream/31149;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/167394, chr7-CpG: 95/Downstream/114629
Upstream sequence
CCCAGGCCATTCAGGACAACAGAGAAGCCTCCCATCACAGAGCCTATTCCCATACAAGCTGTCCTCACACGTTCTTCTGGTCTCAAACTTTCCTCCAGAT
Downstream sequence
TTATCTTATGCATTCATTCGTTTACATGCTCGATTACCATTTGGTGAGCATCTTTTCATGCAGGCTCTGGTCAAAATAAAAAGAAAAGAGCAAGGAGTAA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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