Basic Information
VIS ID
TVIS30000491
Fusion event
HIV-ACTR3C integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr7
Cytoband
q36.1
Reference genome
GRCh37/hg19
Start
149791141/150094052 (Hg38)
End
149791141/150094052 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA7I
Target gene
ACTR3C
miRNAs that regulate target gene
hsa-mir-379-3p ; hsa-mir-487a-3p ; hsa-mir-127-3p ; hsa-mir-539-3p
Nearest miRNA
hsa-mir-10399/Upstream/2715931; hsa-mir-153-2/Downstream/1144369;
Nearest TSS
ENST00000635602/Upstream/31963; ENST00000471872/Downstream/155008;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/44672, chr7-CpG: 87/Downstream/125945
Nearby gene
ACTR3C(-153160) ;
Upstream sequence
tttcttggtaaccttatgatgcaaatacaaccatagcctcggttttctggtgaggagaggaagcagagcacagataggtaaaataacttaggcagagacc
Downstream sequence
caccagctgtccgtgcagagctcagctttcaactcgggccacgtggcctcagagccTACCCTAGTGATCGAATTACACAATCCTTTGCTTTGCTGGTGGA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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