Basic Information
VIS ID
TVIS30000501
Fusion event
HIV-PPP1R16A integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145725408/144500025 (Hg38)
End
145725408/144500025 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
PPP1R16A
miRNAs that regulate target gene
hsa-mir-1-3p
Nearest miRNA
hsa-mir-10400/Upstream/37486; hsa-mir-6850/Downstream/291906;
Nearest TSS
ENST00000518652/Upstream/999; ENST00000528430/Downstream/1064;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/21506, chr8-CpG: 111/Downstream/52
Upstream sequence
TCTAGGACAGCCGATGGGCCCCAAGGCTGCCTCTCCCAGCAGCAGGTGGACAGGGTGCCTCCTGAGGGGCAGCCCTGGGCTGAGGGGCCCTGGCGGGGAC
Downstream sequence
TTCTCCAAGTGAGGAGCCTGGCAAGCGGGGAAGGGCCTTGTGCCCAGCACCCCGTCCGTCTTCCCTGCAGTGGCGCCAATCTCCTGGCGGTCAACACCGA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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