Basic Information
VIS ID
TVIS30000513
Fusion event
HIV-RABL6 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
139708636/136814184 (Hg38)
End
139708636/136814184 (Hg38)
Orient
+
Location type
Intronic
Target gene
RABL6
miRNAs that regulate target gene
hsa-mir-1226-3p ; hsa-mir-425-5p ; hsa-mir-484 ; hsa-mir-191-5p ; hsa-mir-222-3p ; hsa-mir-10a-5p ; hsa-let-7e-5p
Nearest miRNA
hsa-let-7a-1/Upstream/67214; hsa-mir-3621/Downstream/16773;
Nearest TSS
ENST00000422679/Upstream/5336; ENST00000436380/Downstream/7145;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/5413, chr9-CpG: 86/Downstream/7027
Upstream sequence
CTTCAGCAGCTTGAAAATCCACATAGTCAGATTTCCTTGTCATACCCATTCTGACATCCACAACAGCAAGATCATTTTTAGCAAAAATATCATGGATACT
Downstream sequence
AGtttttgtttttctttctttttcgagacagggtcttgctctgttacccaggctggagtgcaatggtgctcactgcagcttccacctcccgggttcaagt
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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