Basic Information
VIS ID
TVIS30000515
Fusion event
HIV-LARP4B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr10
Cytoband
p15.3
Reference genome
GRCh37/hg19
Start
969989/924049 (Hg38)
End
969989/924049 (Hg38)
Orient
-
Location type
Intronic
Target gene
LARP4B
miRNAs that regulate target gene
hsa-mir-103a-3p ; hsa-mir-30a-5p ; hsa-let-7d-5p ; hsa-mir-218-5p ; hsa-mir-4642 ; hsa-mir-542-3p ; hsa-mir-4504 ; hsa-mir-3622b-5p ; hsa-mir-642b-3p ; hsa-mir-642a-3p ; hsa-mir-4715-5p ; hsa-mir-106a-3p ; hsa-mir-191-3p ; hsa-mir-603 ; hsa-mir-6776-3p ; hsa-mir-3941 ; hsa-mir-4789-3p ; hsa-mir-8485 ; hsa-mir-6822-3p ; hsa-mir-21-3p ; hsa-mir-3591-3p ; hsa-mir-4768-5p ; hsa-mir-6833-3p ; hsa-mir-6873-3p
Nearest miRNA
hsa-mir-5699/Upstream/282271; hsa-mir-107/Downstream/1151970;
Nearest TSS
ENST00000439456/Upstream/20534; ENST00000435531/Downstream/7427;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/114104, chr10-CpG: 134/Downstream/7300
Upstream sequence
AATTTTAAAGCATTTTTAggccaggtgcaatggctcacatctgtaatcccaacactctgggactgcttgaacccaggaattcgagaccagactgggcaac
Downstream sequence
atagtgagacccgccacctctacaaaaaaaaattttttttttaattagccaggtgtggtggcatgcacccatgggtcccagctactcgggaggctaaggt
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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