Basic Information
VIS ID
TVIS30000522
Fusion event
HIV-EXOC6 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr10
Cytoband
q23.33
Reference genome
GRCh37/hg19
Start
94746156/92986399 (Hg38)
End
94746156/92986399 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D
Target gene
EXOC6
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-31-5p ; hsa-mir-4668-3p ; hsa-mir-6739-3p ; hsa-mir-6853-3p ; hsa-mir-1206
Nearest miRNA
hsa-mir-107/Upstream/3393572; hsa-mir-1287/Downstream/3077916;
Nearest TSS
ENST00000439456/Upstream/58025; ENST00000458552/Downstream/11075;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/137117, chr10-CpG: 255/Downstream/73870
Upstream sequence
AATAACTATGATGGTGGGATAATTTTACTAATGCAAATAAAATTTATTCGAAGTTAATCTAGAAAAAAGTTAGTGTTTATCTAGGGTCTATTCCAGTCTT
Downstream sequence
CCAGAAGAGTTCTTTGtctggttaacacaactgctgtcccactgcctactagggttaattaggttgaccagcctggctagtgagtatctgcttcttccat
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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