Basic Information
VIS ID
TVIS30000525
Fusion event
HIV-ATE1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr10
Cytoband
q26.13
Reference genome
GRCh37/hg19
Start
123556557/121797042 (Hg38)
End
123556557/121797042 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Target gene
ATE1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-130b-3p ; hsa-let-7b-5p
Nearest miRNA
hsa-mir-107/Upstream/1838450; hsa-mir-202/Downstream/619923;
Nearest TSS
ENST00000439456/Upstream/6816; ENST00000618971/Downstream/105496;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/187823, chr10-CpG: 125/Downstream/130415
Upstream sequence
CAAAATAAATACATGGAAAATATCTTAGTTTAACAAAATGTAACAGAATTCAGCCTAAAAATTAAAATCATTTTGATAGCCAGAGGTTAAAAGTTATCTC
Downstream sequence
ACTATCATATCTTACTGGATAACAATGAACACAAGTATAAAAGGACATATGTACGTGGAAAAATTGGATTTCACAATTAGTAATAATTTCAGCAGAGATA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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