Basic Information
VIS ID
TVIS30000527
Fusion event
HIV-PDE3B integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
14697775/14676229 (Hg38)
End
14697775/14676229 (Hg38)
Orient
+
Location type
Intronic
Target gene
PDE3B
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-128-3p ; hsa-mir-124-3p ; hsa-mir-93-5p ; hsa-mir-16-5p ; hsa-mir-562 ; hsa-mir-3119 ; hsa-mir-4735-5p ; hsa-mir-5683
Nearest miRNA
hsa-mir-210/Upstream/2512462; hsa-let-7a-2/Downstream/1293304;
Nearest TSS
ENST00000527297/Upstream/31969; ENST00000532740/Downstream/22610;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/31101, chr11-CpG: 68/Downstream/215125
Upstream sequence
cttttgtgaaatgttcaagtcttttgctaattttaaaattggattgttcattttcaaaaaattactggtttgtagttgttttagAcagtcatgcgttgct
Downstream sequence
taacagtgaggatatgttctgagaaatgtgttaggtgatttcgtcattgtgcaaacatcacagagtacttacacaaacctagatgttacagcctactcca
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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