Basic Information
VIS ID
TVIS30000530
Fusion event
HIV-CSTF3 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
p13
Reference genome
GRCh37/hg19
Start
33140791/33119245 (Hg38)
End
33140791/33119245 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11E
Target gene
CSTF3
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-24-3p ; hsa-mir-378a-3p ; hsa-mir-132-3p
Nearest miRNA
hsa-mir-210/Upstream/4641697; hsa-let-7a-2/Downstream/1822592;
Nearest TSS
ENST00000527297/Upstream/33341; ENST00000531870/Downstream/42176;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/78945, chr11-CpG: 24/Downstream/42196
Upstream sequence
ACTACATACAAATTGAAAACTGCTGTTTAAAAATATTAGCAATTGTATTATCACTGGACAAAAGCCTTTAGTCATTTCCTCTACTTGAGATATTCTAGTT
Downstream sequence
CACTAATCAAGACAATCTTTCCCATTTTGATAGAGATTCCTATCAGAATACTATTTCTCTTACTTAATTTTCAGTGTCATCCAATGAATTCACATTTTTT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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