Basic Information
VIS ID
TVIS30000534
Fusion event
HIV-P2RY6 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
q13.4
Reference genome
GRCh37/hg19
Start
72975739/73264694 (Hg38)
End
72975739/73264694 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
P2RY6
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-1269b ; hsa-mir-1269a ; hsa-mir-4515 ; hsa-mir-1288-3p ; hsa-mir-4740-5p ; hsa-mir-3120-5p ; hsa-mir-6760-3p
Nearest miRNA
hsa-mir-10392/Upstream/481102; hsa-let-7a-2/Downstream/1134543;
Nearest TSS
ENST00000527297/Upstream/155; ENST00000544437/Downstream/536;
Nearest CpG islands
chr11-CpG: 32/Target, None/Upstream, None/Downstream
Upstream sequence
GCAGCGCCTGGGCGAGTGACATCTGGGCCGGACCAGCTGGTGCTGCGCGGCGCAGGTAAGGGCGTGCGCGGGCAGGGACAGGGGTAAGGGGTGCCGGGGC
Downstream sequence
GCGGGGATACAGGGAGGCCTGCCCACTCCAGGGTCGCGGCCAGTCAGGGCGGGTGCCGGGGGTGAGTCCCTGCATATGTGTGTAGTGTGGGCAATGTGTA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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