Basic Information
VIS ID
TVIS30000535
Fusion event
HIV-UVRAG integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
q13.5
Reference genome
GRCh37/hg19
Start
75721231/76010187 (Hg38)
End
75721231/76010187 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
UVRAG
miRNAs that regulate target gene
hsa-mir-203a-3p ; hsa-mir-92a-3p ; hsa-mir-130b-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-32-5p ; hsa-mir-615-3p ; hsa-mir-92b-3p ; hsa-mir-33a-5p ; hsa-mir-301a-3p ; hsa-mir-205-5p ; hsa-mir-183-5p ; hsa-mir-203a-5p
Nearest miRNA
hsa-mir-10392/Upstream/675001; hsa-let-7a-2/Downstream/3391835;
Nearest TSS
ENST00000527297/Upstream/30127; ENST00000525183/Downstream/105713;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/194306, chr11-CpG: 79/Downstream/154206
Nearest cancer related gene
UVRAG(TSG, No orient, 0)
Upstream sequence
AAGACATTCACAAAAATGTGTTTTGATATTAATTTTAGGCAAAGTTGTGGTATCTTGAAGCCCATGGCGCATCATTTTCCTCattgattcatttagtaaa
Downstream sequence
catattgagtacttttgtcccgtaccagtttcctgggatacagaACAttattcattgaaaaaaatgttcattgaacacctaaatgccaggcacatgatgc
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
Curate