Basic Information
VIS ID
TVIS30000538
Fusion event
HIV-DCUN1D5 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr11
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
102954366/103083637 (Hg38)
End
102954366/103083637 (Hg38)
Orient
+
Location type
Intronic
Target gene
DCUN1D5
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-16-5p ; hsa-mir-149-5p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-6831-3p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-548s ; hsa-mir-6734-5p ; hsa-mir-1226-5p ; hsa-mir-6834-5p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6721-5p ; hsa-mir-3926 ; hsa-mir-4722-5p ; hsa-mir-3616-3p ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-3190-5p ; hsa-mir-6849-3p ; hsa-mir-4433a-3p ; hsa-mir-3614-5p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-299-5p ; hsa-mir-3149 ; hsa-mir-3152-3p ; hsa-mir-3658 ; hsa-mir-3910 ; hsa-mir-483-3p ; hsa-mir-539-5p
Nearest miRNA
hsa-mir-10392/Upstream/1563732; hsa-let-7a-2/Downstream/766269;
Nearest TSS
ENST00000527297/Upstream/798; ENST00000533027/Downstream/5681;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/630606, chr11-CpG: 66/Downstream/7908
Upstream sequence
TTAAGAAAATTTAAAAAGCAGCAAAGAAATACTCCATTAGTATCAATCACAAGTTAGTACAAAAACTCAAACCAATCCATTAAAAAAAAAATTCACTGAG
Downstream sequence
AGCCTACTCTGAATAAAATTTTTGACAATGCATGAATATGAAAAAACATAAGGCAGCTGGAGCTTCTTAATCTACTGGAATATCAGAACCAACACAAAGT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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