Basic Information
VIS ID
TVIS30000544
Fusion event
HIV-DGKA integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr12
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
56332311/55938527 (Hg38)
End
56332311/55938527 (Hg38)
Orient
-
Location type
Exonic
Target gene
DGKA
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-484
Nearest miRNA
hsa-mir-1244-3/Upstream/1601213; hsa-let-7i/Downstream/1255977;
Nearest TSS
ENST00000382841/Upstream/268; ENST00000549085/Downstream/26;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/6088, chr12-CpG: 34/Downstream/28156
Upstream sequence
CTCTTTGTTTCCCCCATATTCTGGTATGAATTCTTTGGGTATCTCTCACAAACTGACCCTGGCCCCCCTAAAACACCCCACAGTCACCTTCAAGCTGTAC
Downstream sequence
GACACGGACAGAAATGGGATCCTGGACAGCTCAGTGAGTTGGGGACCCTGTATGCTGGGCAAGGGAATATGTGTTAATTTGTCTGCACCCTCCTGCCCCA
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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