Basic Information
VIS ID
TVIS30000551
Fusion event
HIV-FRY integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr13
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
32607392/32033255 (Hg38)
End
32607392/32033255 (Hg38)
Orient
+
Location type
Intronic
Target gene
FRY
miRNAs that regulate target gene
hsa-mir-132-3p ; hsa-mir-489-3p ; hsa-mir-3913-3p ; hsa-mir-3973 ; hsa-mir-425-5p ; hsa-mir-802 ; hsa-mir-4517 ; hsa-mir-559 ; hsa-mir-548y ; hsa-mir-548w ; hsa-mir-548o-5p ; hsa-mir-548j-5p ; hsa-mir-548i ; hsa-mir-548h-5p ; hsa-mir-548d-5p ; hsa-mir-548c-5p ; hsa-mir-548bb-5p ; hsa-mir-548b-5p ; hsa-mir-548ay-5p ; hsa-mir-548au-5p ; hsa-mir-548as-5p ; hsa-mir-548ar-5p ; hsa-mir-548aq-5p ; hsa-mir-548ap-5p ; hsa-mir-548am-5p ; hsa-mir-548ak ; hsa-mir-548ae-5p ; hsa-mir-548ad-5p ; hsa-mir-548ab ; hsa-mir-548a-5p ; hsa-mir-511-5p ; hsa-mir-4474-5p ; hsa-mir-6830-3p ; hsa-mir-4509 ; hsa-mir-4744 ; hsa-mir-186-5p ; hsa-mir-3133 ; hsa-mir-148b-3p
Nearest miRNA
hsa-mir-2276/Upstream/7870751; hsa-mir-1267/Downstream/7630779;
Nearest TSS
ENST00000623511/Upstream/1616; ENST00000436046/Downstream/27609;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1489, chr13-CpG: 23/Downstream/278032
Upstream sequence
CCAAACAGCATTCTTTACTTGTCATAGCTATAAATCATTTAACTTGGACTCATTATTTTTATAATACTTTACACTCAAGGATGAATCTTCCTTTGTCTAT
Downstream sequence
CTGCTCTTTGATTAATGAAAAGAATTTGACATACAGTGTTCTTTATGGAGCAGTTTTCCAATAACTGAAAAAACTCACTTTTGAGTTGACATCAGTACGT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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