Basic Information
VIS ID
TVIS30000552
Fusion event
HIV-ZC3H13 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr13
Cytoband
q14.13
Reference genome
GRCh37/hg19
Start
46594672/46020537 (Hg38)
End
46594672/46020537 (Hg38)
Orient
-
Location type
Exonic
Target gene
ZC3H13
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-374b-3p ; hsa-mir-6794-3p ; hsa-mir-6837-3p ; hsa-mir-6754-3p ; hsa-mir-412-3p ; hsa-mir-520f-5p ; hsa-mir-4509 ; hsa-mir-4744 ; hsa-mir-4639-3p ; hsa-mir-4698
Nearest miRNA
hsa-mir-2276/Upstream/1824337; hsa-mir-1267/Downstream/3975878;
Nearest TSS
ENST00000623511/Upstream/50; ENST00000606351/Downstream/32148;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/306458, chr13-CpG: 51/Downstream/31782
Upstream sequence
CTGAAACTCACCATCTCTATTAGTTTCCCATTCTACATTTTCTTCTTCACTTTCTGGAGTTCTTTCCTTAGTGATTTTTATGTCTTCCTTTTCCCTATGT
Downstream sequence
CTCCCTCTTGAAGATTCTTTCTAAAAAAGTACATACATACATTCAGATTACTATATTTTTAAAAATTATGAGGTAGTTTATTGTAATAAGAGAACATTTT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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