Basic Information
VIS ID
TVIS30000566
Fusion event
HIV-COA8 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr14
Cytoband
q32.33
Reference genome
GRCh37/hg19
Start
104050641/103584304 (Hg38)
End
104050641/103584304 (Hg38)
Orient
-
Location type
Intronic
Target gene
COA8
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-331-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-7150 ; hsa-mir-3692-3p ; hsa-mir-548au-3p ; hsa-mir-449b-5p ; hsa-mir-449a ; hsa-mir-34c-5p ; hsa-mir-34a-5p ; hsa-mir-2115-5p ; hsa-mir-382-3p ; hsa-mir-640 ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-186-3p ; hsa-mir-6513-3p ; hsa-mir-8079 ; hsa-mir-1245a ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-1307-3p ; hsa-mir-4638-5p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-6890-3p ; hsa-mir-4655-5p
Nearest miRNA
hsa-mir-1185-1/Upstream/1044578; hsa-mir-12121/Downstream/533101;
Nearest TSS
ENST00000550708/Upstream/12548; ENST00000557079/Downstream/3698;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/20970, chr14-CpG: 188/Downstream/43910
Upstream sequence
cacctcaatatgttcagtagcccggatgctctctgaaccccatggtttagggatttttatggaggtctcatgaggtaggcatggttgattaaatcattgg
Downstream sequence
ccgttggtaattagctcaatctctactccctctcctttccccaaaactgaaagttttgagcttccaatcaaggcttggtctttccggcccccatcccgaa
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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