Basic Information
VIS ID
TVIS30000569
Fusion event
HIV-UBR1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr15
Cytoband
q15.2
Reference genome
GRCh37/hg19
Start
43319347/43027149 (Hg38)
End
43319347/43027149 (Hg38)
Orient
-
Location type
Intronic
Target gene
UBR1
miRNAs that regulate target gene
hsa-mir-93-5p ; hsa-mir-193b-3p ; hsa-mir-92a-3p ; hsa-mir-25-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-1827 ; hsa-mir-6806-3p ; hsa-mir-3928-5p ; hsa-mir-873-5p ; hsa-mir-6796-3p ; hsa-mir-4695-5p
Nearest miRNA
hsa-mir-1233-1/Upstream/827483; hsa-mir-10393/Downstream/766510;
Nearest TSS
ENST00000557528/Upstream/486; ENST00000570109/Downstream/656;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/105746, chr15-CpG: 34/Downstream/106555
Upstream sequence
AGTAGGGAGACATCATAACCTTAGTAATTTGCAAATGAAAATATACTACTGAATCCTTTATATAGTACTATAAGGAAAATCACTGAGGTCAAAAGGAGTA
Downstream sequence
CTCCATATTTGTTCTAAACATTAAACAGCTTTTGGTTTCTATCCAATCTCTAAGTCGAATATTTCAATGAACATTACTAGATCATAAGAAAAGCTATACC
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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