Basic Information
VIS ID
TVIS30000581
Fusion event
HIV-PARN integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr16
Cytoband
p13.12
Reference genome
GRCh37/hg19
Start
14693760/14599903 (Hg38)
End
14693760/14599903 (Hg38)
Orient
-
Location type
splicing
Target gene
PARN
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-377-3p ; hsa-mir-8485 ; hsa-mir-521 ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-376a-2-5p
Nearest miRNA
hsa-mir-1225/Upstream/290532; hsa-mir-11401/Downstream/301605;
Nearest TSS
ENST00000527434/Upstream/7826; ENST00000570219/Downstream/10796;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/296685, chr16-CpG: 55/Downstream/29842
Upstream sequence
CATTCTAAAGGAGATGAAATGATTAATCTGCAATGATAATTAGATACTTCACCTGAAATAGTATGTTCTGCAATCTTGCTAAAAAGTCTGGCTCACTTAC
Downstream sequence
CGAATTAGCAATGGCGTGAATGACTCTAGAAAATCCCACAGCATCATTCAGCTCCTCCTAATTAAAAAAATATATACATATGTATTATTGATGTATAAAT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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