Basic Information
VIS ID
TVIS30000583
Fusion event
HIV-METTL9 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr16
Cytoband
p12.2
Reference genome
GRCh37/hg19
Start
21635474/21624153 (Hg38)
End
21635474/21624153 (Hg38)
Orient
-
Location type
Intronic
Target gene
METTL9
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-26b-5p
Nearest miRNA
hsa-mir-1225/Upstream/118018; hsa-mir-11401/Downstream/2578963;
Nearest TSS
ENST00000527434/Upstream/6255; ENST00000564733/Downstream/27716;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/23780, chr16-CpG: 37/Downstream/39802
Upstream sequence
ccaccgtgcccggtcCTTTTCTGTATAGTTATTCAGATATGAAGATTCTCAAGTATGAAATATGTCTTTCCTGGGAACGGAAATGTGCTCAAAGGTCATA
Downstream sequence
AGTTATCAATGGAAATTATTTTATACCACTCCCAGCCATTTTTAAGAATAGAAGGGATCCTAGGAATAGAAAACATTAATTATATGATGCATTTTTTGAT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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