Basic Information
VIS ID
TVIS30000595
Fusion event
HIV-MYH10 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
8508839/8605521 (Hg38)
End
8508839/8605521 (Hg38)
Orient
+
Location type
Intronic
Target gene
MYH10
miRNAs that regulate target gene
hsa-mir-1274a ; hsa-mir-106b-3p ; hsa-mir-92b-3p ; hsa-mir-505-3p ; hsa-mir-197-3p ; hsa-mir-26a-5p ; hsa-mir-23a-3p ; hsa-mir-200a-3p
Nearest miRNA
hsa-mir-1253/Upstream/418517; hsa-mir-10226/Downstream/3476378;
Nearest TSS
ENST00000595228/Upstream/628; ENST00000585297/Downstream/25196;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/128300, chr17-CpG: 188/Downstream/24165
Upstream sequence
atatccacaattatctaaaaagggtattaaaatactcttcttggccaggcacggtggctcacgcctgtaatcccagcactttgagaggccgaggagggtg
Downstream sequence
gatcacaaggtcaggagttcaagactagcctggccaagatggtgaaaccctgtctctactaaaaatacaaaaattagccgggcacagtggcaggcgcctg
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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