Basic Information
VIS ID
TVIS30000601
Fusion event
HIV-AP2B1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
q12
Reference genome
GRCh37/hg19
Start
33990727/35663708 (Hg38)
End
33990727/35663708 (Hg38)
Orient
+
Location type
Intronic
Target gene
AP2B1
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-744-5p ; hsa-mir-532-3p ; hsa-mir-615-3p ; hsa-mir-106b-5p ; hsa-mir-99a-5p ; hsa-mir-92a-3p ; hsa-mir-19b-3p ; hsa-mir-188-5p ; hsa-mir-623 ; hsa-mir-4780 ; hsa-mir-6866-3p ; hsa-mir-4325 ; hsa-mir-7703 ; hsa-mir-656-5p ; hsa-mir-6780b-3p ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-214-3p ; hsa-mir-31-5p ; hsa-mir-3619-5p ; hsa-mir-3665 ; hsa-mir-3688-5p ; hsa-mir-424-5p ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-497-5p ; hsa-mir-503-5p ; hsa-mir-646 ; hsa-mir-6809-5p ; hsa-mir-6815-5p ; hsa-mir-6838-5p ; hsa-mir-6865-5p ; hsa-mir-761
Nearest miRNA
hsa-mir-1180/Upstream/3313506; hsa-mir-10226/Downstream/1370037;
Nearest TSS
ENST00000595228/Upstream/13058; ENST00000603498/Downstream/50083;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/66583, chr17-CpG: 74/Downstream/67822
Upstream sequence
ggtgcatttgaagctgcagaataaatatggctcattgtcttgcagtgtcagtcttacttgatggtaaataatgtaaacagaatatacactggtgtgttac
Downstream sequence
cacttagaatgtaaaattgcatgactttaagataaaaAATACAGCTTGCTTGCCCTGGGCCTCTTGATGGTGTACATCCCAGGTCCCTGAGTATATGAGT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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