Basic Information
VIS ID
TVIS30000608
Fusion event
HIV-DGKE integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
q22
Reference genome
GRCh37/hg19
Start
54931228/56853867 (Hg38)
End
54931228/56853867 (Hg38)
Orient
+
Location type
Intronic
Target gene
DGKE
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-548f-3p ; hsa-mir-548e-3p ; hsa-mir-548az-3p ; hsa-mir-548ar-3p ; hsa-mir-548a-3p ; hsa-mir-6807-5p ; hsa-mir-1306-5p ; hsa-mir-556-5p ; hsa-mir-744-3p ; hsa-mir-6805-3p ; hsa-mir-5691 ; hsa-mir-455-3p ; hsa-mir-7641 ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-3194-3p ; hsa-mir-4695-3p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-3607-5p ; hsa-mir-572 ; hsa-mir-1304-3p ; hsa-mir-6890-3p ; hsa-mir-433-3p ; hsa-mir-7154-5p ; hsa-mir-4530 ; hsa-mir-922 ; hsa-mir-6858-3p ; hsa-mir-5582-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-3199 ; hsa-mir-365a-5p ; hsa-mir-365b-5p ; hsa-mir-4258 ; hsa-mir-4707-3p ; hsa-mir-4740-3p ; hsa-mir-552-3p ; hsa-mir-764 ; hsa-mir-8052
Nearest miRNA
hsa-mir-10226/Upstream/6085137; hsa-mir-1250/Downstream/37403;
Nearest TSS
ENST00000595228/Upstream/9848; ENST00000570738/Downstream/8319;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/18758, chr17-CpG: 89/Downstream/59604
Upstream sequence
taaaactagaattaccatatgttccagcaatcccatttatagatatatacccaaaggaattgaaatcagtatatcaaacagatgtccatgctgccatgtt
Downstream sequence
cattgcagcattatgtacaatagccaagatgcagaaataacctaagtgcccatcagtgaatgaatggtttttttaagtatgccatatatacacaatggaa
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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