Basic Information
VIS ID
TVIS30000611
Fusion event
HIV-CYTH1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr17
Cytoband
q25.3
Reference genome
GRCh37/hg19
Start
76769280/78773198 (Hg38)
End
76769280/78773198 (Hg38)
Orient
+
Location type
Intronic
Target gene
CYTH1
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-335-5p ; hsa-mir-26b-5p ; hsa-mir-34a-5p ; hsa-mir-1827 ; hsa-mir-3940-3p
Nearest miRNA
hsa-mir-10226/Upstream/1376144; hsa-mir-1250/Downstream/933978;
Nearest TSS
ENST00000595228/Upstream/36231; ENST00000587434/Downstream/9074;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/270205, chr17-CpG: 155/Downstream/8230
Upstream sequence
ctgggattacaagcatgagccaccatgcccagccTGAAACTGAACAGTTTATCATTATAACCCAGACCAATACAATCTGTTTAATTCACAGGAAggtgtg
Downstream sequence
gtggctcatgcctgtaatcctagtactttaggaagccaaggcaggagaatcacttgaggccaggagttcaagaccagcctgggtaacacagtgagaccct
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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