Basic Information
VIS ID
TVIS30000616
Fusion event
HIV-DSG2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr18
Cytoband
q12.1
Reference genome
GRCh37/hg19
Start
29102683/31522720 (Hg38)
End
29102683/31522720 (Hg38)
Orient
+
Location type
Intronic
Target gene
DSG2
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-124-3p ; hsa-mir-1-3p ; hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-15b-5p ; hsa-mir-126-5p ; hsa-mir-944 ; hsa-mir-494-3p ; hsa-mir-510-3p ; hsa-let-7f-2-3p ; hsa-mir-1185-2-3p ; hsa-mir-1185-1-3p ; hsa-mir-556-3p ; hsa-mir-5589-3p ; hsa-mir-5700 ; hsa-mir-4789-5p ; hsa-mir-98-3p ; hsa-let-7f-1-3p ; hsa-let-7b-3p ; hsa-let-7a-3p ; hsa-mir-4666a-3p ; hsa-mir-381-3p ; hsa-mir-300 ; hsa-mir-8064 ; hsa-mir-215-3p ; hsa-mir-3607-5p ; hsa-mir-6760-3p ; hsa-mir-603 ; hsa-mir-8485
Nearest miRNA
hsa-mir-1-2/Upstream/1223760; hsa-mir-122/Downstream/4069017;
Nearest TSS
ENST00000575820/Upstream/24500; ENST00000432547/Downstream/34185;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/24157, chr18-CpG: 145/Downstream/161989
Upstream sequence
gtttctttttaaaatgtggctactagaagatttaaaattacataAAAACAGCACCATTCTAGGGCCTCTCCTATCAGGGTTCTGTTTACTAGAGGTTCCT
Downstream sequence
AAAACATTTCTCAGTTTGCAGTTCTCTAATGAAACATTAGGAGGCTCCTCCACGGCTAGTACGTAGGAGGCAGTGAGGAAAGGGATGAAAATAGGAATCC
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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