Basic Information
VIS ID
TVIS30000625
Fusion event
HIV-KIAA0355 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr19
Cytoband
q13.11
Reference genome
GRCh37/hg19
Start
34815023/34324118 (Hg38)
End
34815023/34324118 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
KIAA0355
miRNAs that regulate target gene
hsa-mir-20a-3p ; hsa-mir-149-5p ; hsa-let-7e-5p ; hsa-mir-3687 ; hsa-mir-3157-3p ; hsa-mir-8075 ; hsa-mir-18b-3p ; hsa-mir-4708-3p ; hsa-mir-93-3p ; hsa-mir-451b ; hsa-mir-124-3p ; hsa-mir-6893-3p ; hsa-mir-370-3p
Nearest miRNA
hsa-mir-10395/Upstream/13924764; hsa-let-7e/Downstream/798582;
Nearest TSS
ENST00000633603/Upstream/58550; ENST00000588974/Downstream/24344;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/68819, chr19-CpG: 56/Downstream/35048
Upstream sequence
TCCTTCCCCTGCCTCATGACAGCAGAGGAGGTGCCCTCTCCTCCTGTCCAGGCTTGCCCCGTGCTGGCCTTGCCCCCATCCTCGAGGGCCCAGCTTCTGT
Downstream sequence
GGTGCGACCTAGTGTTTTCTCTCCCTCATCCTCAGCCTGTTCCCACCAGTACACAAAGATGCTTCCCACAGAAAAGTCCACTCTGCCCTGCCCTGTTTCT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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