Basic Information
VIS ID
TVIS30000630
Fusion event
HIV-PRR12 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50127695/49624438 (Hg38)
End
50127695/49624438 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
PRR12
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-615-3p ; hsa-mir-320a ; hsa-mir-34a-5p ; hsa-mir-92a-3p ; hsa-mir-16-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6515-5p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-6848-5p ; hsa-mir-7847-3p ; hsa-mir-6846-5p ; hsa-mir-6825-5p ; hsa-mir-939-5p ; hsa-mir-1343-5p ; hsa-mir-3175 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-6797-5p ; hsa-mir-149-3p ; hsa-mir-1249-5p ; hsa-mir-766-5p ; hsa-mir-6133 ; hsa-mir-6130 ; hsa-mir-6129 ; hsa-mir-6127 ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-194-3p ; hsa-mir-6805-5p ; hsa-mir-4786-5p ; hsa-mir-6849-3p ; hsa-mir-1273g-3p ; hsa-mir-4666b ; hsa-mir-5011-3p ; hsa-mir-6076 ; hsa-mir-6797-3p ; hsa-mir-6807-5p
Nearest miRNA
hsa-mir-10395/Upstream/123570; hsa-let-7e/Downstream/57679;
Nearest TSS
ENST00000633603/Upstream/3989; ENST00000601038/Downstream/2001;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/8219, chr19-CpG: 68/Downstream/15528
Upstream sequence
GGATGGTGCTGAGAATTCTGGGATAGGTGGTTAGGATGGGGCTGAGAATTCTGGGATAGATAGTTAGGATGGGGCTGAGAATTCTGGGGTAGGTGGTTAG
Downstream sequence
GATGGTGCTGAAAATTTtggggtaggtggttaggatggggctgggaattctggggtaggtggttaggatggggctgagaattctgggatagatggttagg
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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