Basic Information
VIS ID
TVIS30000632
Fusion event
HIV-ZNF331 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr19
Cytoband
q13.42
Reference genome
GRCh37/hg19
Start
54063941/53560687 (Hg38)
End
54063941/53560687 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
ZNF331
miRNAs that regulate target gene
hsa-mir-20a-5p ; hsa-mir-4474-3p ; hsa-mir-7108-5p ; hsa-mir-664b-3p ; hsa-mir-579-3p ; hsa-mir-6815-3p ; hsa-mir-5696 ; hsa-mir-6828-5p ; hsa-mir-4729 ; hsa-mir-6510-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-31-5p ; hsa-mir-661 ; hsa-mir-873-3p ; hsa-mir-6860 ; hsa-mir-612 ; hsa-mir-5189-5p ; hsa-mir-3187-5p ; hsa-mir-1285-3p ; hsa-mir-766-3p ; hsa-mir-939-3p ; hsa-mir-6849-3p ; hsa-mir-5586-3p ; hsa-mir-508-5p
Nearest miRNA
hsa-let-7e/Upstream/1278794; hsa-mir-10394/Downstream/105992;
Nearest TSS
ENST00000633603/Upstream/5200; ENST00000376650/Downstream/71369;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/5687, chr19-CpG: 86/Downstream/87135
Upstream sequence
ctgtcatagaggtcagaagtctgaagtgggtctcaccgggctaaaaccaggttgttggaggctgtaggagatattctgtgtccttgcttttgctggcttc
Downstream sequence
tagacgccgcccacactccttagttcgtgaccccttcttccatcagcaaagcctgaaaagacaagtcctttttccgtcacaccactctgaccctcctcct
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
Curate