Basic Information
VIS ID
TVIS30000642
Fusion event
HIV-SLC25A17 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
41205155/40809151 (Hg38)
End
41205155/40809151 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
SLC25A17
miRNAs that regulate target gene
hsa-mir-196a-5p ; hsa-mir-526b-5p ; hsa-mir-642a-5p ; hsa-mir-766-5p ; hsa-mir-4469 ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4496
Nearest miRNA
hsa-mir-1286/Upstream/2820298; hsa-let-7a-3/Downstream/4732;
Nearest TSS
ENST00000624155/Upstream/28896; ENST00000614001/Downstream/10165;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/19739, chr22-CpG: 43/Downstream/9980
Upstream sequence
tatggtttaaaaaatatagcttatgtatgttaacatgtaatggatgtattttacctttttttttttgtagaggcgagacaacattggaattttaggtatg
Downstream sequence
agcaaccacacccagctaatgtatttttaatgatttttaatgaattaacaaatatcttggccgggctcagtggctcatgcctgtaatcctagcactttgg
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
Curate