Basic Information
VIS ID
TVIS30000644
Fusion event
HIV-L3MBTL2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
41606733/41210729 (Hg38)
End
41606733/41210729 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
L3MBTL2
miRNAs that regulate target gene
hsa-mir-744-5p ; hsa-mir-484 ; hsa-mir-5587-5p ; hsa-mir-4793-5p ; hsa-mir-6890-3p ; hsa-mir-8063 ; hsa-mir-4668-3p
Nearest miRNA
hsa-mir-1281/Upstream/118163; hsa-let-7a-3/Downstream/42263;
Nearest TSS
ENST00000624155/Upstream/1033; ENST00000486331/Downstream/6894;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/5257, chr22-CpG: 125/Downstream/26819
Upstream sequence
acttttgtatttttagtagaggcggggtttcaccatgtcggccaggctggtctcaaactcctgaactcaggtgatccacccacctcagcttcccaaagtg
Downstream sequence
ctgggattacaggagtgagccactgtgcccggccCTAGTCTAATTTCAAATTGTGACTTCACTCATTCTTTCATATAACTAATGTGTATTCAGCACAGAT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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