Basic Information
VIS ID
TVIS30000645
Fusion event
HIV-PPP6R2 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr22
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50808564/50370135 (Hg38)
End
50808564/50370135 (Hg38)
Orient
-
Location type
Intronic
Target gene
PPP6R2
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-93-5p ; hsa-mir-19b-3p ; hsa-mir-149-5p ; hsa-mir-92a-3p
Nearest miRNA
hsa-let-7a-3/Upstream/407196; hsa-mir-12114/Downstream/37307;
Nearest TSS
ENST00000624155/Upstream/26804; ENST00000473283/Downstream/1937;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/26555, chr22-CpG: 20/Downstream/36594
Upstream sequence
accacatccCACCTTTTTGATTTGTATATAAAATGTAAaaatatgcaaaagtagagaaaacataattaacatctatgtacccatcacctaacttcgacag
Downstream sequence
tgatcgacactttttttttatttTGAAAGATCTGATTTTATTTTCTGAATCAAAAGTAAGTGTATTCATGTTAAATTTAGAATGTTTTAGCTTTCCATTG
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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