Basic Information
VIS ID
TVIS30000649
Fusion event
HIV-ALG13 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chrX
Cytoband
q23
Reference genome
GRCh37/hg19
Start
110993207/111749979 (Hg38)
End
110993207/111749979 (Hg38)
Orient
-
Location type
Intronic
Target gene
ALG13
miRNAs that regulate target gene
hsa-let-7e-5p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-526b-5p ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-3607-3p ; hsa-mir-1183 ; hsa-mir-548m
Nearest miRNA
hsa-let-7f-2/Upstream/1667761; hsa-mir-105-1/Downstream/1030739;
Nearest TSS
ENST00000429181/Upstream/5133; ENST00000485371/Downstream/2767;
Nearest CpG islands
None/Target, chrX-CpG: 62/Upstream/67932, chrX-CpG: 19/Downstream/331875
Upstream sequence
taggtcatgcctttatcaccttgtccctgaacagttagagtagcttctccattggtctcactgctctggtactattccactttgtgtctgttcctagctc
Downstream sequence
agaactcttcagtgattctttGGTTTCTGTAGATTAAAGTTCAACAGACTAAGTATGGCATTTATGACTTTCCACAATCTAGTCTCTATTCCAACCTTAT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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