Basic Information
VIS ID
TVIS30000657
Fusion event
HIV-KHDRBS1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
p35.2
Reference genome
GRCh37/hg19
Start
32485507/32019906 (Hg38)
End
32485507/32019906 (Hg38)
Orient
-
Location type
Intronic
Target gene
KHDRBS1
miRNAs that regulate target gene
hsa-mir-877-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-27b-3p ; hsa-mir-34a-5p ; hsa-mir-92a-3p ; hsa-mir-203a-3p ; hsa-mir-204-3p
Nearest miRNA
hsa-mir-12136/Upstream/261171; hsa-mir-101-1/Downstream/67043;
Nearest TSS
ENST00000473358/Upstream/5724; ENST00000466321/Downstream/52125;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/4924, chr1-CpG: 80/Downstream/52698
Upstream sequence
tgtcgctcacgctggagtgcagtggcgcgatcttggctgactgctacctctacctttcggtttcaagcagttctcctgcctcagcctcccgagtaggtgg
Downstream sequence
gattacaggcgcccaccaccatgcccggctgatttttgtatttttagtagagatggggtttcaccgtgttggccaggctggtctcaaattcctgaccatg
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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