Basic Information
VIS ID
TVIS30000665
Fusion event
HIV-PRRC2C integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr1
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
171489411/171520272 (Hg38)
End
171489411/171520272 (Hg38)
Orient
-
Location type
Intronic
Target gene
PRRC2C
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-342-5p ; hsa-mir-324-3p ; hsa-mir-320a ; hsa-mir-149-5p ; hsa-mir-218-5p ; hsa-mir-10b-5p ; hsa-mir-10a-5p ; hsa-mir-100-5p ; hsa-mir-20a-5p ; hsa-mir-19a-3p ; hsa-mir-3163 ; hsa-mir-181a-5p ; hsa-mir-181b-5p ; hsa-mir-181c-5p ; hsa-mir-181d-5p ; hsa-mir-221-5p ; hsa-mir-1263 ; hsa-mir-8073 ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-5579-3p ; hsa-mir-4536-5p ; hsa-mir-593-5p ; hsa-mir-7851-3p ; hsa-mir-619-3p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-3924 ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-607 ; hsa-mir-3671 ; hsa-let-7a-2-3p ; hsa-let-7c-3p ; hsa-let-7g-3p ; hsa-mir-202-5p ; hsa-mir-223-3p ; hsa-mir-302f ; hsa-mir-4302 ; hsa-mir-4448 ; hsa-mir-4697-3p ; hsa-mir-4780 ; hsa-mir-493-5p ; hsa-mir-592 ; hsa-mir-597-5p ; hsa-mir-623 ; hsa-mir-6733-3p ; hsa-mir-6772-3p ; hsa-mir-6780b-3p ; hsa-mir-6834-3p
Nearest miRNA
hsa-mir-101-1/Upstream/418466; hsa-mir-1182/Downstream/618526;
Nearest TSS
ENST00000473358/Upstream/8240; ENST00000480806/Downstream/2243;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/34172, chr1-CpG: 26/Downstream/150535
Upstream sequence
ggctagtctcgatctcctgacttgaggtgatccttcctcctcggcctcccaaagtgctgggattacaggcgtgagccaccgtgcctggccATTAAACGTT
Downstream sequence
TTCCTAAAAGAAGTTTGGGAGTATGCTGACCTGGCCTTGAAAAATGATTTATACCCAATTACTTTTTTTCTAATCATTTTCAAATTGTGCTACCAAAGAC
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
Curate