Basic Information
VIS ID
TVIS30000669
Fusion event
HIV-DGUOK integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr2
Cytoband
p13.1
Reference genome
GRCh37/hg19
Start
74177076/73949949 (Hg38)
End
74177076/73949949 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2E
Target gene
DGUOK
miRNAs that regulate target gene
hsa-mir-34a-5p ; hsa-mir-297
Nearest miRNA
hsa-mir-1285-2/Upstream/3696944; hsa-mir-10b/Downstream/1140863;
Nearest TSS
ENST00000437798/Upstream/23041; ENST00000441217/Downstream/31412;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/22795, chr2-CpG: 171/Downstream/34138
Upstream sequence
TTACCAGATGCTCTTTTGGTTGTAGAAATAAGCAGGGGGCAAAGCTGGTTTGATTTTTAGCTTTAGCTTTCTTTTATCTGAACTAGAAACTCAGCAGCAG
Downstream sequence
AGGAAGCAAGCAAGCAGGAGCTCATAATGCATTTTGCAGGAGAGTCTGCTTTCTTAGTAATACTGAAATTAGTAGGAAATGCATTTTCTGCTCCATAGAG
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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