Basic Information
VIS ID
TVIS30000671
Fusion event
HIV-REV1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr2
Cytoband
q11.2
Reference genome
GRCh37/hg19
Start
100099502/99483040 (Hg38)
End
100099502/99483040 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA2S ; FRA2A
Target gene
REV1
miRNAs that regulate target gene
hsa-mir-96-5p ; hsa-mir-21-5p ; hsa-mir-17-5p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106b-5p ; hsa-mir-20b-5p ; hsa-mir-519d-3p ; hsa-mir-155-5p
Nearest miRNA
hsa-mir-1285-2/Upstream/2684687; hsa-mir-10b/Downstream/1826410;
Nearest TSS
ENST00000437798/Upstream/20252; ENST00000434301/Downstream/6933;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/145103, chr2-CpG: 202/Downstream/6041
Upstream sequence
tgggaggaggaggttgcagtgaaccaagatcatgccatagcactccagcctgggcgacaagggcaaaactccgtttcaaaaaaaaaaaaaaaaaTTTTTT
Downstream sequence
TTTTGTTACGGTCTTTAAGATATTGAAGAAGAAATTGTTAAAACATTTGTAAAGTTCAGAACTGTCCAGGTTAAATGCTTTAAAAAAAAAGGCTTAAAAT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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