Basic Information
VIS ID
TVIS30000675
Fusion event
HIV-PMS1 integration
Validated
No
Detection method
QiaQuick PCR and Sequencing
Data source
download(RID)
Sample type
Cell line
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2016
PubMed ID
26912621
Virus Sequence
Virus name
HIV
Reference genome
K03455.1
Host Sequence
Chromosome
chr2
Cytoband
q32.2
Reference genome
GRCh37/hg19
Start
190665339/189800613 (Hg38)
End
190665339/189800613 (Hg38)
Orient
+
Location type
Intronic
Target gene
PMS1
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-15a-5p
Nearest miRNA
hsa-mir-10b/Upstream/667502; hsa-mir-1244-1/Downstream/16982621;
Nearest TSS
ENST00000437798/Upstream/8803; ENST00000483293/Downstream/17514;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/15855, chr2-CpG: 29/Downstream/21401
Upstream sequence
CATTTTGGGGGAAAGGAGTTCACTTTTTAATCTTAAGGAATATTCCTTAGCACTCAGAAAGAATTGAGGTTTCATATATAGAAAAAATATATTTTCAAGA
Downstream sequence
CTAGCTTATTTTGAAACTTTTTAGATGAAAATTACAGTGAATGCAATAAAAATTAGTAATTTGGTTATTTTATCTACCAAACTAACTGATGCATATAATT
Reference
Sunshine, S., et al. HIV Integration Site Analysis of Cellular Models of HIV Latency with a Probe-Enriched Next-Generation Sequencing Assay. J Virol,2016, 90(9): 4511-4519.
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